For instance, a process that acidifies blood will be neutralized by the bicarbonate ions thus minimizing the change in pH. A process that alkalizes blood will be neutralized by the equilibrium concentration of carbonic acid.
In a titration experiment, a buret is used to administer a known concentration of NaOH to a solution of carbonic acid. The pH of the solution is measured throughout the entire titration reaction using a pH meter. A titration curve is then generated relating the change in pH with respect to the volume of NaOH added to the solution.