Fade lentigines with dermabrasion. Much like a chemical peel, this cosmetic procedure removes the surface layer of your skin. But instead of an acid, a rotating brush sands away the epidermis of your face, leaving a controlled wound. As the area heals, new skin forms that lacks the melanin clusters.
Talk to your doctor about cryotherapy. The Cleveland Clinic offers this option to improve the appearance of age spots, stating that the application of liquid nitrogen can effectively destroy the melanin causing the brown spots on the skin.