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Definition of Gamma Globulin

Annually, this condition may progress to multiple myeloma in 1% of these individuals. A variant of monoclonal gammopathy of undetermined significance is asymptomatic or smoldering plasma cell myeloma, in which the diagnostic criteria for multiple myeloma are present but no related organ damage is observed.

Circulating micro RNAs may be a potential biomarker for distinguishing healthy people from those with multiple myeloma or related conditions. The risk of malignant transformation of monoclonal gammopathy of undetermined significance into multiple myeloma is higher in females than in males.

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