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Shigella Bacteria: Overview and Pictures

Expression of the mechanisms encoded on the virulence plasmid are thermoregulated such that strains become invasive when growing at 37°C but not at 30°C, and regulation is by both plasmid and chromosomally located elements.

Plasmid-encoded proteins are required for bacteria to break free from cellular endosomes and for the migration between epithelial cells.

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